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Paul Y. Cao
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| B.S. Nanjing University of Science & Technology, 2001 M.S. Duke University, 2003 Ph.D. Duke University, 2006 |
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Schedule for Fall Semester 2013
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Office Hours:
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My research interest is System Biology (It took quite some time to find what I really like to do).
System Biologists try to decipher the complex relationships among a large number of biological components. Contrary to the "reductionist"
approach, system biology focuses on the study of a biological system in an integral manner. Unfortunately,
existing engineering/mathematics tools are not suitable to give us an understandable picture of the biological
system which is highly uncertain yet being very robust. So new mathematics/statistics tools must be invented to simultaneously model hierarchy, uncertainty and complexity. To me, the lack of competent mathematical models is the bottle neck in the development of the system biology.
Some interesting papers on system biology
1. Hood, L., Systems biology: integrating technology, biology, and computation. Mechanisms of Ageing and Development, 2003. 124(1): p. 9-16.
2. Kitano, H., Systems biology: A brief overview. Science, 2002. 295(5560): p. 1662-1664.
3. Kitano, H., Biological robustness. Nat Rev Genet, 2004. 5(11): p. 826-837.
4. Lazebnik, Y., Can a Biologist Fix a Radio, Cancer Cell, 2002. 2(3):p. 179-182.
My research is focused on the inference of genetic pathways from microarray and sequence data. I am also working on a new system biology model, CMAP, which uses linguistic variables to model the interactions among biological, chemical, or mechanical entities.
See my publication list and professional activities here
Some interesting papers on system biology
1. Hood, L., Systems biology: integrating technology, biology, and computation. Mechanisms of Ageing and Development, 2003. 124(1): p. 9-16.
2. Kitano, H., Systems biology: A brief overview. Science, 2002. 295(5560): p. 1662-1664.
3. Kitano, H., Biological robustness. Nat Rev Genet, 2004. 5(11): p. 826-837.
4. Lazebnik, Y., Can a Biologist Fix a Radio, Cancer Cell, 2002. 2(3):p. 179-182.
My research is focused on the inference of genetic pathways from microarray and sequence data. I am also working on a new system biology model, CMAP, which uses linguistic variables to model the interactions among biological, chemical, or mechanical entities.
See my publication list and professional activities here
Coming Soon!